domingo, 5 de julio de 2009

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure

“The Seventh Report of the Joint National Committee on Prevention, Detection,
Evaluation, and Treatment of High Blood Pressure” provides a new
guideline for hypertension prevention and management. The following are
the key messages: (1) In persons older than 50 years, systolic blood pressure
(BP) of more than 140 mm Hg is a much more important cardiovascular
disease (CVD) risk factor than diastolic BP; (2) The risk of CVD, beginning
at 115/75 mm Hg, doubles with each increment of 20/10 mm Hg; individuals
who are normotensive at 55 years of age have a 90% lifetime risk for
developing hypertension; (3) Individuals with a systolic BP of 120 to 139
mm Hg or a diastolic BP of 80 to 89 mm Hg should be considered as prehypertensive
and require health-promoting lifestyle modifications to prevent
CVD; (4) Thiazide-type diuretics should be used in drug treatment for
most patients with uncomplicated hypertension, either alone or combined
with drugs from other classes. Certain high-risk conditions are compelling
indications for the initial use of other antihypertensive drug classes (angiotensin-
converting enzyme inhibitors, angiotensin-receptor blockers, -blockers,
calcium channel blockers); (5) Most patients with hypertension will require
2 or more antihypertensive medications to achieve goal BP (140/90
mm Hg, or 130/80 mm Hg for patients with diabetes or chronic kidney
disease); (6) If BP is more than 20/10 mm Hg above goal BP, consideration
should be given to initiating therapy with 2 agents, 1 of which usually should
be a thiazide-type diuretic; and (7) The most effective therapy prescribed by
the most careful clinician will control hypertension only if patients are motivated.
Motivation improves when patients have positive experiences with
and trust in the clinician. Empathy builds trust and is a potent motivator.
Finally, in presenting these guidelines, the committee recognizes that the
responsible physician’s judgment remains paramount.

Articulo completo en este link: http://jama.ama-assn.org/cgi/reprint/289.19.2560v1.pdf

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